The microbe is so very small: You cannot take him out at all.
Messieurs, c'est les microbes qui auront le dernier mot." (Gentlemen, it is the microbes who will have the last word.)
Most life on Earth is microbes. we've only just scratched the surface of the microbial realm. Probably less than .1% of microbes have been classified let alone cultured or had their genes sequenced, so really that microbial realm is a mystery.