The use of the word 'plantation' is terribly unwise. It will just reinforce the view most Americans have of Hillary Clinton as being very liberal.
He is obviously a single-issue candidate, and they do not do terribly well in the presidential process.
Frist has managed to work himself into the worst of both worlds. He has alienated moderates because of his positions on Terri Schiavo. Then he has alienated conservatives on embryonic stem cell research.