Molecular Quotations

The idea would be in my mind - and I know it sounds strange - is that the most important advances in medicine would be made not by new knowledge in molecular biology, because that's exceeding what we can even use. It'll be made by mathematicians, physicists, computer scientists, figuring out a way to get all that information together.

According to the belief, molecules closer together than 200 nanometers could not be told apart with focused light. This is because, in a packed molecular crowd, the molecules shout out their fluorescence simultaneously, causing their signal, their voices, to be confused.

When we consider the fact that nearly three-quarters of the surface of the globe is covered by oceanic water, we begin to realise that the molecular scattering of light in liquids may possess an astronomical significance, in fact contribute in an important degree to the observed albedo of the earth.

The fundamental importance of the subject of molecular diffraction came first to be recognized through the theoretical work of the late Lord Rayleigh on the blue light of the sky, which he showed to be the result of the scattering of sunlight by the gases of the atmosphere.

The whole edifice of modern physics is built up on the fundamental hypothesis of the atomic or molecular constitution of matter.

Chemical compounds of carbon can exist in an infinite variety of compositions, forms and sizes. The naturally occurring organic substances are the basis of all life on Earth, and their science at the molecular level defines a fundamental language of that life.

Some of the most significant advances in molecular biology have relied upon the methodology of genetics. The same statement may be made concerning our understanding of immunological phenomena.

The really big difference is that what you make with a molecular machine can be completely precise, down to the tiniest degree of detail that can exist in the world.

The moment I saw the model and heard about the complementing base pairs I realized that it was the key to understanding all the problems in biology we had found intractable - it was the birth of molecular biology.

It is fortunate that molecular synthesis also serves the utilitarian function of producing quantities of rare or novel substances which satisfy human needs, especially with regard to health, and the scientific function of stimulating research and education throughout the whole discipline of chemistry.

We have to accept that we are just machines. That's certainly what modern molecular biology says about us.

Polymeric materials in the form of wood, bone, skin and fibers have been used by man since prehistoric time. Although organic chemistry as a science dates back to the eighteenth century, polymer science on a molecular basis is a development of the twentieth century.

But while doing that I'd been following a variety of fields in science and technology, including the work in molecular biology, genetic engineering, and so forth.

I cannot imagine a more enjoyable place to work than in the Laboratory of Molecular Biology where I work.

Cancer is like the common cold; there are so many different types. In the future we'll still have cancer, but we'll detect it very, very early, so that it won't kill anybody. We'll zap it at the molecular level decades before it grows into a tumor.

I decided that the University of Sussex in Brighton was a good place for this work because it had a strong tradition in bacterial molecular genetics and an excellent reputation in biology.

We can grow crops less expensively because molecular manufacturing technology is inherently low cost.

I became fascinated by the then-blossoming science of molecular biology when, in my senior year, I happened to read the papers by Francois Jacob and Jacques Monod on the operon theory.

You can find academic and industrial groups doing some relevant work, but there isn't a focus on building complex molecular systems. In that respect, Japan is first, Europe is second, and we're third.

I decided to pursue graduate study in molecular biology and was accepted by Professor Itaru Watanabe's laboratory at the Institute for Virus Research at the University of Kyoto, one of a few laboratories in Japan where U.S.-trained molecular biologists were actively engaged in research.

In my early work, our molecular views of telomeres were first focused on the DNA.

The other advantage is that in conventional manufacturing processes, it takes a long time for a factory to produce an amount of product equal to its own weight. With molecular machines, the time required would be something more like a minute.

In an age of molecular genomics, it is ever more apparent that the fingerprints of evolution are pressed deeply into human DNA, just as they are into the genomes of every other organism. Biologists understand this, and so do students who study the science of life.

During the decade following the discovery of the double-helical structure of DNA, the problem of translation - namely, how genetic information is used to synthesize proteins - was a central topic in molecular biology.

I've been around a long time, and I've been interested in memory for a long time. And one of my earlier interests in molecular biology of memory led me to define the switch that converts short term to long term memory.

A molecular manufacturing technology will let us build molecular surgical tools, and those tools will, for the first time, let us directly address the problems at the very root level.

It turns out all molecular and biological systems have speeds of the atoms move inside them; the fastest possible speeds are determined by their molecular vibrations, and this speed is about a kilometre per second.

Our approach to medicine is very 19th-century. We are still in the dark ages. We really need to get to the molecular level so that we are no longer groping about in the dark.

We are proud to be teaming up with Mr. Glenn and the Glenn Foundation. Like us, Paul is dedicated to finding the molecular answers to the aging process so we can understand the mechanisms of normal aging and develop interventions to delay its onset and decline, thereby extending the healthful years of human life.

To our knowledge, the current study is the first to identify a molecular mechanism that blocks both retrieval and reconsolidation of any type of memory. While much remains to be understood concerning the cellular processes underlying the effects of ERK in drug-stimulus associations and other types of learning and memory, the present findings offer hope for treating cue-elicited relapse in addicts.

There are more studies, the risk estimates are more consistently elevated, and they're higher than they were for lung cancer. Plus, there's all these toxicology studies and molecular biology they didn't have back then.

The process of star formation is obscured because it takes place in these dense molecular clouds, so it's not yet directly observable. Astrophysicists believe that magnetic fields play a strong role in regulating the star formation by affecting the shape of these molecular clouds.

This progress in the molecular analysis of the cell cycle led to more interest being taken in my work and as a consequence to greater competition.

The proteins act as molecular spies that tell us what is happening within cells in the living mouse.

Siemens continues to set the standard in advanced molecular imaging research. Accuracy and efficiency are imperative in this arena, and with this new reconstruction and calibration technology, Siemens will deliver the highest quality multi-pinhole SPECT solution to its customers.

Since the cells will adhere to the surface at locations where the complementary nucleotide sequences match, we can program cell adhesion events with a virtually unlimited number of possible coding options. The DNA effectively serves as a molecular barcode on the surface of living cells.

Molecular chirality plays a key role in science and technology. In particular, life depends on molecular chirality in that many biological functions are inherently dissymmetric.

Molecular chemistry, the chemistry of the covalent bond, is concerned with uncovering and mastering the rules that govern the structures, properties and transformations of molecular species.

Much of my work in biology has been driven by my early training in chemistry. When studying a new chemical compound, the first and most important thing is to determine its detailed molecular structure.

Much of modern molecular biology and microbiology has been based on the effort to decipher the basic code of life, which is made up of four nucleotides: adenine, thymine, cytosine, and guanine.

No one had ever labeled the components to follow them over time, to see one clock as it ticks away in a single cell. All the biochemistry and molecular biology that had been done on this had been piecing together information from dead flies.

Nature - how, we don't know - has technology that works in every living cell and that depends on every atom being precisely in the right spot. Enzymes are precise down to the last atom. They're molecules. You put the last atom in, and it's done. Nature does things with molecular perfection.

My cooking philosophy, what I try to do, is to make a cuisine where the produce and the product shines, compared to some current trends that are maybe more adding additional things, like molecular cuisine, with a lot of additives and chemicals, which are now showing that they could be bad for your health.

Retinoic acid can positively reverse signs of aging on a molecular level and help rejuvenate the skin. The problem is it's irritating,

One of the major lessons in all of biochemistry, cell biology and molecular medicine is that when proteins operate at the sub cellular level, they behave in a certain way as if they're mechanical machinery.

I find the paper to be an impressive demonstration of the molecular basis of an atavism.

Four and a half billion years ago, all of the matter of the solar system, including us, was part of a giant molecular cloud. Genesis is providing the chemical composition of that solar nebula. ...The material is still stored for us in the surface of the sun.

I envision devices that detect disease much earlier than conventional detection methods. It could eventually be possible to initiate treatment at this very early stage using implanted devices that communicate with cells at the molecular level.

We are gaining information on the differences and similarities between viral mechanisms and eukaryotic mechanisms. Getting to the molecular details of these gets to the possibility of learning one mechanism versus the other so you can try and stop (the virus from attacking) the human cell.

There is an ongoing conflict between 'whole organism' and 'molecular' approaches to studying insects. Friction has evolved because molecular biology is taking over a tremendous amount of resources, including funding and space within universities.

Our study provides a fundamentally new level of analysis by which we can better understand the actions of cocaine in brain-reward regions at the molecular level. It also points to new potential treatments for addiction.

Our work demonstrates a fundamental error in the current challenges to Darwinism. New techniques allowed us to see how ancient genes and their functions evolved hundreds of millions of years ago. We found that complexity evolved piecemeal through a process of Molecular Exploitation -- old genes, constrained by selection for entirely different functions, have been recruited by evolution to participate in new interactions and new functions.

Our Board and management team are united in the belief that we must take bold action now to lead the emerging era of molecular medicine with leading positions in both genetic and protein analysis.

People need to be a little more lenient with him. There is a lot being thrown at him. There's no fear, which is good, and he's doing a nice job with the analysis. We're trying to work in the play-by-play, and people might think it's easy, but it's not. It's not molecular science, either, but it's not easy. And he's getting the pacing. It's almost a poetic measure of speech. You get the rhythm, and people get into the rhythm with you. I'll be very surprised if he isn't doing two innings of play-by-play by the end of the season.

Such information at the molecular level is vital to gain insights into the pathogenesis of malaria, and potentially offers the opportunity to develop better drugs.

Most of the people who claim to be doing systems biology are really studying simple and complex molecular machines and how they function, and that is an aspect of systems biology; but it isn't. It's the networks that really capture and store and transmit and integrate and modulate and finally end up executing the biological information as it is.

We need to understand why younger women are more likely to get the disease, why there are molecular differences in lung cancer between men and women, and why there are treatment differences between men and women.

We are looking at the very material from which each of us came. In a very real sense, you are looking at your atomic and molecular ancestry.

What we see strongly suggests that the magnetic field is indeed helical. If it is so, then this tells us a lot about the role magnetic fields might play in molecular clouds and star formation. It would be a major piece of evidence in trying to solve this mystery of how stars form.

This report is the first to demonstrate evidence of enhancements in memory reconsolidation in the brain. Understanding these molecular mechanisms may provide critical insights into psychiatric disorders.

When children's minds are open to new ideas and concepts at the age of six, they could be taught the basics of molecular structure, how Oxygen and Hydrogen and Carbon join up to make ever-day substances. By the age of 14, their minds are already doubtful of new ideas which suggest something fundamentally different to what they know, and they can no longer be inspired into exploring science.

With the completion of the human genome, and the numerous recent discoveries in molecular and cell biology, exciting new approaches to diagnose and treat diseases are rapidly being investigated.

Essentially, every technology you have ever heard of, where electrons move from here to there, has the potential to be revolutionized by the availability of molecular wires made up of carbon. Organic chemists will start building devices. Molecular electronics could become reality.

I see this as the new frontier in our understanding of child development. We don't know the molecular mechanism by which a mother's behavior reaches down to inhibit or elicit the expression of a gene, but clearly that's happening.

The way I see it, there are three types of studies in science: one that moves a theory along, one that closes it and another that opens a new door altogether. This one opens a new chapter, introducing an entirely new molecular candidate for the study of anxiety, and we're going to be hearing a lot about it in the next 10 years.

I've always been intellectually curious. I love doing homework, and I try to learn and improve myself every day. Molecular genetic biology interests me because it's applicable to myself in that it deals with the human body.

Our approach to materials chemistry is to use sophisticated design principles and reaction chemistry to prepare new types of successful matter, ... Our goal is to control the shapes of new materials with the same level of precision that we exercise when controlling the stereo chemical relationships in a natural products synthesis. The precise molecular engineering of materials (nanotechnology) is a quintessential component in the emergence of PSI-TEC's high-tech product line.

advances in probability theory, computer science, the concept of information, molecular biology and the philosophy of science.

Studying organisms at a molecular level was totally compelling because it was moving from being a naturalist, which was the 19th-century kind of science, to being very focused and really getting to the heart of these molecules.

At Xavier I was a biology and pre-med double major, but they handle pre-med differently out here and I am not in the program yet. My classes are totally different. I went from molecular biology and other science courses to English classes like Eroticism and Love in the Middle Ages.

The molecular scar induced by chronic stress in the hippocampus, and perhaps elsewhere in the brain, can't be easily reversed. To really cure depression, we probably need to find new treatments that can remove the silencer molecules.

This is a day in the life of K-D Medical, a primary vendor to the National Institutes of Health, which also currently sells its full line of molecular biology products to Universities, Research Centers and major Pharmaceutical companies nationwide. While we may not produce products that directly lead to headlines about cures for diseases, we produce the bacterial and yeast growth media, the microbiological buffers and reagents that lead to major advances in science in public health. For instance, we are very involved in the research involving anthrax, which is feared to be a possible biological weapon of choice for terrorists.

Although there has been solid theory on the matter for quite some time, these results provide the first definitive proof at the molecular level that sexual reproduction magnifies the efficiency of natural selection in eliminating deleterious mutations from populations.

The research is aiming to make a molecular assembler, one machine that can build, on a molecular scale, anything.

As we better understand the molecular pathways that account for newborns' susceptibility to infections, we can leverage them to enhance their immune defenses.

As water comes off the rings, it is split by sunlight; the resulting hydrogen and atomic oxygen are then lost, leaving molecular oxygen.

For both mice and men, social status is important; for mice, losing to a dominant mouse usually means that they avoid the dominant and they avoid social situations. These new findings add to a growing literature on the molecular basis of social behavior, helping us to know where as well as how social information is encoded in the brain.

For every two horses in our sample we were able to get a molecular measure of their relationship. It turned out that that was on average 47%,

It's terrifying the way molecular biology has become more and more jargon ridden. But I strongly believe that my book can be read by the intelligent layman. I want everyone who bought a copy of 'A Brief History of Time' to buy a copy of 'Genome'.

Data from several cultivation-independent, molecular experiments led us to suspect that Archaea could be involved in the marine nitrogen cycle. Subsequently having the organism isolated in the lab allowed us to confirm our suspicions,

Supramolecular chemistry, the designed chemistry of the intermolecular bond, is rapidly expanding at the frontiers of molecular science with physical and biological phenomena.

It is the quest for an understanding of hair cells at a molecular level that drives our research. We would like to understand how hair cells work, why they are vulnerable and why in mammals hair cells do not regenerate.

It just takes two or three pinches of bone powder to find molecular evidence. We have protein sequences from material believed to be in range of half a million years old. We are carefully working our way back in time.

Evolution, cell biology, biochemistry, and developmental biology have made extraordinary progress in the last hundred years - much of it since I was weaned on schoolboy biology in the 1930s. Most striking of all is the sudden eruption of molecular biology starting in the 1950s.

If you get infertility, then you know that the molecule is required for fertility, and this is our 'smoking gun.' Basically, we are asking the animal to tell us what it requires for its fertility, and then we try to understand how it works on a molecular level.

In research, I wanted to establish the medicinal chemistry/bioassay conjugation as an academic pursuit, as exciting to the imagination as astrophysics or molecular biology.

I naively thought that we could have a molecular definition for life, come up with a set of genes that would minimally define life. Nature just refuses to be so easily quantified.

Genomics, nanobiotechnology and breakthroughs in molecular biology, genetics and biological engineering have opened up a broad spectrum of opportunities and challenges for manipulating microbial and plant systems to produce novel organic compounds and to meet part of the U.S. and world energy needs. Opportunities abound for integrating these advances in engineering and science into regional, national and global efforts to develop sustainable industries and communities.

If everything works out -- if IGF-2 status is tied to colon cancer risk in people and the blood test is workable -- then IGF-2 status could be the colon cancer equivalent of cholesterol levels as a risk factor for heart disease. We've never had a broad molecular screening tool like that for any cancer.

I developed an interest in nuclear magnetic resonance, which was then emerging as a powerful technique for studying molecular structure.

For the first time, we've shown that the difference in the rate of molecular evolution between humans and chimpanzees is very small, but significant, suggesting the evolution of human-specific life history traits is very recent.

The holy grail of our research is to convince those cells to regenerate, but now, we need to first understand what the composition of hair cells are and how they develop. We believe that a molecular understanding of the function of hair cells is needed to ultimately prevent hearing loss, and stimulate the regeneration of hair cells in mammals.

The conservative statement is that telomere length is a biomarker, but it's probably not passive. There are some very intimate relationships between things such as molecular markers for inflammation and telomere health.

The MCC maintain that the epoxy that is used as adhesive to glue the covering to the wood of the blade, produces some molecular reaction, whereby the carbon graphite can be considered as part of the blade. The fact that 60 per cent of bats with manufactured coverings use such epoxy does not seem to have been a consideration.

The laws of nature are simply such that in a molecular cloud there are just a few big clumps and quite many more smaller clumps.