Neil Buckholtz Quotations

We presently don't have fully validated imaging or biomarker measures that can help us monitor the development or progression of Alzheimer's in living people. This study represents one step in the progress being made toward identifying clinically useful biological measures for Alzheimer's disease.

This research is intriguing because it associates genetic risk for dementia with twins' cognitive deficits, even in the absence of dementia. The differences in cognitive deficits between identical and fraternal twins are also important, suggesting that the twins who were more similar genetically had the greater risk.

It's really critical that we find ways to prevent, or at least delay the onset of, cognitive decline. Once the pathology is established in the brain, it's very difficult to treat. We need better ways to prevent the disease in the first place, which could make a huge difference for the future.