David Madden Gray Quotations

It appears that age-related cognitive changes are the result of combined influences on the gray matter and the white matter.

Based on past studies, we expected greater activation in the frontal and parietal regions in the older adults, especially when top-down attention was required. We also hypothesized that an age-related related decline in the white matter integrity in the frontal part of the brain would correlate with changes in gray matter activation.