While the lab plays an enormous role, research is also influenced by inner peace of mind and one's family environment, depending on what stage of one's life and career a scientist is at.
Until 1985, when my lab found the protein they are made of, aquaporins hadn't yet been identified. There had been a controversy in biology for more than 100 years about how water moved through cells.
My wife and I have four children, and none of them are in lab science, so clearly I returned home at night and presented a fairly unattractive example of a scientific life.